Santa Teresa is the name of a neighbourhood in the city of Rio de Janeiro, Brazil. It is located on top of the Santa Teresa hill, by the centre of Rio, and is famous for its winding, narrow streets which are a favourite spot for artists and tourists.

The neighbourhood originated around the Santa Teresa Convent, built in the 1750s on the Desterro hill. At the end of the 19th and early 20th century it was an upper class borough, as testified by its magnificent mansions, many of which are still standing.